Single-Cell Dissociation and Characterization in the Murine Retina and Optic Nerve.

@article{Choi2018SingleCellDA,
  title={Single-Cell Dissociation and Characterization in the Murine Retina and Optic Nerve.},
  author={Hee Joo Choi and Rui Wang and Tatjana C. Jakobs},
  journal={Methods in molecular biology},
  year={2018},
  volume={1695},
  pages={
          311-334
        }
}
Recent technological advances have extended the range of analytic tools to very small samples. It is now possible to assay the transcriptome, and in some cases even the proteome, of single cells reliably. This allows addressing novel questions, such as the genotype/phenotype relationships of single neurons, heterogeneity within individual cells of the same type, or the basis of differential vulnerability to injury. An important prerequisite for these kinds of studies is the ability to isolate… CONTINUE READING
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