Single‐nucleotide polymorphism, rs1799941 in the Sex Hormone‐Binding Globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: the Tromsø Study

@article{Svartberg2014SinglenucleotidePR,
  title={Single‐nucleotide polymorphism, rs1799941 in the Sex Hormone‐Binding Globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: the Troms{\o} Study},
  author={J. Svartberg and H. Schirmer and T. Wilsgaard and E. Mathiesen and I. Nj{\o}lstad and M-L L{\o}chen and R. Jorde},
  journal={Andrology},
  year={2014},
  volume={2}
}
Low testosterone levels are associated with metabolic and cardiovascular disease risk factor, and have been shown to predict type 2 diabetes mellitus (T2DM), myocardial infarction (MI) and all‐cause mortality. It is not known if these associations are causal or not. Recently, it has been shown that the serum testosterone levels are associated with single‐nucleotide polymorphisms (SNPs), and we therefore studied the associations between one of these SNPs, rs1799941 on the Sex Hormone‐Binding… Expand
23 Citations
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