Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial

@inproceedings{Chevalier2010SingleIT,
  title={Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial},
  author={Xavier Chevalier and J{\"o}rg Jerosch and Philippe Goupille and Nynke van Dijk and Frank P. Luyten and David Lloyd Scott and François Bailleul and Karel Pavelka},
  booktitle={Annals of the rheumatic diseases},
  year={2010}
}
OBJECTIVES The primary objective was to compare a single, 6 ml, intra-articular injection of hylan G-F 20 with placebo in patients with symptomatic knee osteoarthritis. The safety of a repeat injection of hylan G-F 20 was also assessed. METHODS Patients with primary osteoarthritis knee pain were randomly assigned to arthrocentesis plus a 6 ml intra-articular injection of either hylan G-F 20 or placebo in a prospective, double-blind (one injector/one blinded observer) study. RESULTS were… CONTINUE READING