Sindbis virus replicase-based DNA vaccine construct encoding FMDV-specific multivalent epitope gene: studies on its immune responses in guinea pigs.

@article{Dar2012SindbisVR,
  title={Sindbis virus replicase-based DNA vaccine construct encoding FMDV-specific multivalent epitope gene: studies on its immune responses in guinea pigs.},
  author={Pervaiz Ahmed Dar and K Madhan Muthu Ganesh and Govindasamy Nagarajan and S Sarika and Golla Ramalinga Reddy and Veluvarthy Sanyasi Suryanarayana},
  journal={Scandinavian journal of immunology},
  year={2012},
  volume={76 4},
  pages={345-53}
}
Foot-and-mouth disease (FMD) is still a perennial global menace affecting livestock health and production. It is imperative to figure out new ways to curb this disease. In this study, a sindbis virus replicase-based DNA vaccine, pSinCMV-Vac-MEG990, encoding a multivalent epitope gene (representing tandemly linked VP1 C-terminal halves of three foot-and… CONTINUE READING