Simvastatin and vitamin E effects on cardiac and hepatic oxidative stress in rats fed on high fat diet

@article{Abbas2013SimvastatinAV,
  title={Simvastatin and vitamin E effects on cardiac and hepatic oxidative stress in rats fed on high fat diet},
  author={Amr Medhat Abbas and Hussein F. Sakr},
  journal={Journal of Physiology and Biochemistry},
  year={2013},
  volume={69},
  pages={737-750}
}
High fat diet (HFD) is a common cause of metabolic syndrome and type 2 diabetes mellitus. Published data showed that HFD and subsequent dyslipidemia are major triggers for oxidative stress. Forty-eight male Sprague–Dawley rats, weighing 170–200 g, were divided into six groups: control, control with vitamin E (100 mg/kg/day, i.p.), control with simvastatin… CONTINUE READING