Simultaneous two-photon activation of presynaptic cells and calcium imaging in postsynaptic dendritic spines

@inproceedings{Matsuzaki2011SimultaneousTA,
  title={Simultaneous two-photon activation of presynaptic cells and calcium imaging in postsynaptic dendritic spines},
  author={Masanori Matsuzaki and Graham C R Ellis-Davies and Yuya Kanemoto and Haruo Kasai},
  booktitle={Neural systems & circuits},
  year={2011}
}
BACKGROUND Dendritic spines of pyramidal neurons are distributed along the complicated structure of the dendritic branches and possess a variety of morphologies associated with synaptic strength. The location and structure of dendritic spines determine the extent of synaptic input integration in the postsynaptic neuron. However, how spine location or size relates to the position of innervating presynaptic cells is not yet known. This report describes a new method that represents a first step… CONTINUE READING
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