Simultaneous transfer of vascular endothelial growth factor and hepatocyte growth factor genes effectively promotes liver regeneration after hepatectomy in cirrhotic rats.

@article{Oe2004SimultaneousTO,
  title={Simultaneous transfer of vascular endothelial growth factor and hepatocyte growth factor genes effectively promotes liver regeneration after hepatectomy in cirrhotic rats.},
  author={Hideaki Oe and Toshimi Kaido and Hiroaki Furuyama and Atsuo Mori and Mitsutoshi Imamura},
  journal={Hepato-gastroenterology},
  year={2004},
  volume={51 60},
  pages={
          1641-7
        }
}
BACKGROUND/AIMS Liver regeneration in a cirrhotic liver is unsatisfactory. In the course of liver regeneration, non-parenchymal cells such as sinusoidal endothelial cells as well as hepatocytes increase in number while the liver structure and physiological functions are maintained. The aim of this study was to examine whether sufficient liver regeneration could be obtained by the simultaneous, preoperative injection of recombinant adenoviral vectors encoding human vascular endothelial growth… CONTINUE READING

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