Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination.

@article{PaisVieira2013SimultaneousTM,
  title={Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination.},
  author={Miguel Pais-Vieira and Mikhail A. Lebedev and Michael C. Wiest and Miguel A. L. Nicolelis},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2013},
  volume={33 9},
  pages={4076-93}
}
The rat somatosensory system contains multiple thalamocortical loops (TCLs) that altogether process, in fundamentally different ways, tactile stimuli delivered passively or actively sampled. To elucidate potential top-down mechanisms that govern TCL processing in awake, behaving animals, we simultaneously recorded neuronal ensemble activity across multiple cortical and thalamic areas while rats performed an active aperture discrimination task. Single neurons located in the primary somatosensory… CONTINUE READING
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