Simultaneous separation of nitrofuran antibiotics and their metabolites by using micellar electrokinetic capillary chromatography

@article{Wickramanayake2006SimultaneousSO,
  title={Simultaneous separation of nitrofuran antibiotics and their metabolites by using micellar electrokinetic capillary chromatography},
  author={Priyanga U Wickramanayake and Tin C. Tran and J. Hughes and M. Macka and N. Simpson and P. Marriott},
  journal={ELECTROPHORESIS},
  year={2006},
  volume={27}
}
  • Priyanga U Wickramanayake, Tin C. Tran, +3 authors P. Marriott
  • Published 2006
  • Chemistry, Medicine
  • ELECTROPHORESIS
  • Mixtures comprising nitrofuran antibiotics (NFA) and nitrofuran metabolites (NFM) were resolved for the first time by using MEKC. Sodium deoxycholate (SDC) was chosen as the micelle‐forming surfactant. Optimization of separation conditions was achieved by using a central composite experimental design (CCD) approach. Experimental parameters such as concentration ratio of borate to phosphate in the buffer, pH of the running electrolyte and voltage were investigated. The effect of concentration of… CONTINUE READING
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