Simultaneous screening for JAK2 and calreticulin gene mutations in myeloproliferative neoplasms with high resolution melting.

@article{Matsumoto2016SimultaneousSF,
  title={Simultaneous screening for JAK2 and calreticulin gene mutations in myeloproliferative neoplasms with high resolution melting.},
  author={Nariyoshi Matsumoto and Sayaka Mori and Hiroo Hasegawa and Daisuke Sasaki and Hayato Mori and Kazuto Tsuruda and Daisuke Imanishi and Yoshitaka Imaizumi and Tomoko Hata and Norihito Kaku and Kousuke Kosai and Naoki Uno and Yasushi Miyazaki and Katsunori Yanagihara},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2016},
  volume={462},
  pages={166-173}
}
INTRODUCTION Recently, novel calreticulin (CALR) mutations were discovered in Janus kinase 2 (JAK2) non-mutated myelofibrosis (PMF) and essential thrombocythemia (ET) cases, with a frequency of 60-80%. We examined clinical correlations and CALR mutation frequency in our myeloproliferative neoplasms (MPN) cases, and introduce an effective test method for use… CONTINUE READING