Simultaneous release of acetylcholine and ATP from stimulated cholinergic synaptosomes.

@article{Morel1981SimultaneousRO,
  title={Simultaneous release of acetylcholine and ATP from stimulated cholinergic synaptosomes.},
  author={Nicolas Morel and F. M. Meunier},
  journal={Journal of neurochemistry},
  year={1981},
  volume={36 5},
  pages={1766-73}
}
The release of acetylcholine (ACh) and ATP from pure cholinergic synaptosomes isolated from the electric organ of Torpedo was studied in the same perfused sample. A presynaptic ATP release was demonstrated either by depolarization with KCl or after the action of a venom extracted from the annelid Glycera convoluta (GV). The release of ATP exhibited similar kinetics to that of ACh release and was therefore probably closely related to the latter. The ACh/ATP ratio in perfusates after KCl… CONTINUE READING

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