Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study.

@article{Wendt1998SimultaneousRV,
  title={Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study.},
  author={Thomas Georg Wendt and Gerhard G. Grabenbauer and Claus Michael R{\"o}del and H. Jurgen Thiel and Hakan Aydin and Ralf Rainer Rohloff and Thomas P. U. Wustrow and Heiner Iro and Christian Popella and Andreas Schalhorn},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1998},
  volume={16 4},
  pages={
          1318-24
        }
}
PURPOSE A prospective randomized multicenter trial was performed to evaluate the contribution of simultaneously administered chemotherapy (CT) and radiotherapy (RT) in previously untreated patients with unresectable stage III/IV head and neck cancer. PATIENTS AND METHODS Patients with locoregionally advanced head and neck cancer were treated either with RT alone (arm A) or simultaneous RT plus CT (RCT; arm B). RT was identical in both arms and administered in three courses with 13 fractions… CONTINUE READING
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