Simultaneous quantitative determination of calcium leucovorin and parabens in lyophilized ampoules by derivative spectroscopy.

@article{Bertini1992SimultaneousQD,
  title={Simultaneous quantitative determination of calcium leucovorin and parabens in lyophilized ampoules by derivative spectroscopy.},
  author={J Bertini and A Cocchini and F Lamonaca and R Noferini and A Perico},
  journal={Farmaco},
  year={1992},
  volume={47 7-8},
  pages={1105-14}
}
A simple and rapid procedure for quantitation of Calcium Leucovorin and parabens simultaneously in lyophilized ampoules formulation by "zero crossing" first-order derivative spectroscopy was developed. The ampoules content was dissolved in a mixture water/ethanol (50/50) and first-derivative spectra were recorded. The absolute values of the derivative at… CONTINUE READING