Simultaneous quantification of six constituents in Qing-huo-zhi-mai tablet by high-performance liquid chromatography-tandem mass spectrometry.

@article{Wang2015SimultaneousQO,
  title={Simultaneous quantification of six constituents in Qing-huo-zhi-mai tablet by high-performance liquid chromatography-tandem mass spectrometry.},
  author={S. Wang and M. Zhao and Weijing Ding and Congkun Xiang and Yulu Tian and T. Li and Shan Fu and J. Zhang and Q. Wang},
  journal={Journal of chromatographic science},
  year={2015},
  volume={53 1},
  pages={
          24-30
        }
}
A novel sensitive and specific high-performance liquid chromatography-tandem mass spectrometry method was established for the simultaneous determination of six constituents including geniposide, andrographolide, dehydroandrographolide, ophiopogonin D, methylophiopogonanone A and methylophiopogonanone B in Qing-huo-zhi-mai (QHZM) tablet, a well-known Chinese herbal preparation. The chromatographic separation was performed on a C18 column, and the mobile phase was composed of 0.04% acetic acid… Expand

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