Simultaneous quantification of prostate-specific antigen and human glandular kallikrein 2 mRNA in blood samples from patients with prostate cancer and benign disease.

@article{Ylikoski2002SimultaneousQO,
  title={Simultaneous quantification of prostate-specific antigen and human glandular kallikrein 2 mRNA in blood samples from patients with prostate cancer and benign disease.},
  author={Alice Ylikoski and Kim Pettersson and Jussi T Nurmi and Kerttu Irjala and Matti Karp and Hans G Lilja and Timo L{\"o}vgren and Martti J Nurmi},
  journal={Clinical chemistry},
  year={2002},
  volume={48 8},
  pages={1265-71}
}
BACKGROUND Detection or quantification of circulating cancer cells has been proposed as an aid in detection and monitoring of several solid tumors. We investigated the classification accuracy of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) mRNA copy numbers in blood for the differentiation of patients with prostate cancer (PC) and benign disease. METHODS PSA and hK2 mRNA expression was studied in blood samples from 51 men with PC and 19 men with benign disease. Among… CONTINUE READING

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