Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC

@inproceedings{ContrerasSanz2012SimultaneousQO,
  title={Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC},
  author={Alberto Contreras-Sanz and Toby S. Scott-Ward and Hardyal S. Gill and Jennifer C. Jacoby and Rebecca E. Birch and James G Malone-Lee and Kevin Michael Geoffrey Taylor and Claire M. Peppiatt-Wildman and Scott S. P. Wildman},
  booktitle={Purinergic Signalling},
  year={2012}
}
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways. For the first time, we have used an ion-pair reversed-phase high-performance liquid chromatography ultraviolet (UV)-coupled method to rapidly and simultaneously quantify 12 different nucleotides and nucleosides (adenosine triphosphate… CONTINUE READING