Simultaneous multi-patch-clamp and extracellular-array recordings: Single neuron reflects network activity

@inproceedings{Vardi2016SimultaneousMA,
  title={Simultaneous multi-patch-clamp and extracellular-array recordings: Single neuron reflects network activity},
  author={Roni Vardi and Amir Goldental and Shira Sardi and Anton Sheinin and Ido Kanter},
  booktitle={Scientific reports},
  year={2016}
}
The increasing number of recording electrodes enhances the capability of capturing the network's cooperative activity, however, using too many monitors might alter the properties of the measured neural network and induce noise. Using a technique that merges simultaneous multi-patch-clamp and multi-electrode array recordings of neural networks in-vitro, we show that the membrane potential of a single neuron is a reliable and super-sensitive probe for monitoring such cooperative activities and… CONTINUE READING
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