Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes

@inproceedings{Dmitriev2012SimultaneousMA,
  title={Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes},
  author={Petr V. Dmitriev and Ana Barat and Anna Polesskaya and Mary J. O’Connell and Thomas Robert and Philippe Dessen and Thomas Anthony Walsh and Vladimir Lazar and Ahmed Turki and Gilles Carnac and Dalila Laoudj-Chenivesse and Marc Lipinski and Yegor S Vassetzky},
  booktitle={BMC Genomics},
  year={2012}
}
miRNA profiling performed in myogenic cells and biopsies from skeletal muscles has previously identified miRNAs involved in myogenesis. Here, we have performed miRNA transcriptome profiling in human affinity-purified CD56+ myoblasts induced to differentiate in vitro. In total, we have identified 60 miRNAs differentially expressed during myogenic differentiation. Many were not known for being differentially expressed during myogenic differentiation. Of these, 14 (miR-23b, miR-28, miR-98, miR-103… CONTINUE READING