Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.

@article{Kushida1983SimultaneousLC,
  title={Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.},
  author={Kazuhiro Kushida and Kan Chiba and Takashi Ishizaki},
  journal={Therapeutic drug monitoring},
  year={1983},
  volume={5 1},
  pages={127-33}
}
A method for the simultaneous analysis of chloramphenicol and four antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma by high-performance liquid chromatography (HPLC) is described. The method involves a preliminary extraction of 0.1 ml of plasma with diethyl ether containing phenacetin as an internal standard… CONTINUE READING