Simultaneous insulinlike growth factor I and insulin resistance in obese Zucker rats.

@article{Jacob1992SimultaneousIG,
  title={Simultaneous insulinlike growth factor I and insulin resistance in obese Zucker rats.},
  author={Ralph J Jacob and Robert S. Sherwin and Kather ine Greenawalt and Gerald I Shulman},
  journal={Diabetes},
  year={1992},
  volume={41 6},
  pages={691-7}
}
It has recently been shown that the ability of insulinlike growth factor I (IGF-I) to stimulate glucose uptake and to lower circulating amino acid levels is retained in insulin-resistant diabetic BB rats. To examine in vivo effects of IGF-I in obese Zucker rats (another model of insulin resistance) 6 obese and 6 lean rats received euglycemic IGF-I infusions… CONTINUE READING