Simultaneous immunohistochemical expression of HBME-1 and galectin-3 differentiates papillary carcinomas from hyperfunctioning lesions of the thyroid.

@article{Rossi2006SimultaneousIE,
  title={Simultaneous immunohistochemical expression of HBME-1 and galectin-3 differentiates papillary carcinomas from hyperfunctioning lesions of the thyroid.},
  author={Esther Diana Rossi and Marco Raffaelli and Antonino Mule' and Antonella Miraglia and Celestino Pio Lombardi and Fabio Maria Vecchio and G Fadda},
  journal={Histopathology},
  year={2006},
  volume={48 7},
  pages={795-800}
}
AIMS The histological diagnosis is critical for the postsurgical management and follow-up of thyroid malignancies. The differential diagnosis between papillary carcinoma and hyperfunctioning lesions, either with papillary hyperplasia or with a follicular architecture, can create real diagnostic difficulty. The aim of this study was to evaluate the expression of several antibodies considered to be markers of malignancy in malignant and hyperfunctioning thyroid neoplasms and to include the most… CONTINUE READING

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