Simultaneous high-performance liquid chromatographic determination of urinary mandelic and phenylglyoxylic acids as indirect evaluation of styrene exposure.

@article{Laffon2001SimultaneousHL,
  title={Simultaneous high-performance liquid chromatographic determination of urinary mandelic and phenylglyoxylic acids as indirect evaluation of styrene exposure.},
  author={Blanca Laffon and M. Victor Lema and Josefina M{\'e}ndez},
  journal={Journal of chromatography. B, Biomedical sciences and applications},
  year={2001},
  volume={753 2},
  pages={385-93}
}
Styrene is rapidly metabolised to mandelic acid (MA) and phenylglyoxylic acid (PGA), which are excreted in urine. In this work, we have developed a simple, sensitive and specific high-performance liquid chromatographic method with minor sample preparation procedures for the simultaneous determination of MA and PGA in urine of workers exposed to styrene… CONTINUE READING