Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression

@inproceedings{Lin2009SimultaneousGA,
  title={Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression},
  author={Yanzhu Lin and Min Zhang and Libo Wang and Vitara Pungpapong and James C. Fleet and Dabao Zhang},
  booktitle={BMC proceedings},
  year={2009}
}
Genome-wide associations between single-nucleotide polymorphisms and clinical traits were simultaneously conducted using penalized orthogonal-components regression. This method was developed to identify the genetic variants controlling phenotypes from a massive number of candidate variants. By investigating the association between all single-nucleotide polymorphisms to the phenotype of antibodies against cyclic citrullinated peptide using the rheumatoid arthritis data provided by Genetic… CONTINUE READING
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