Simultaneous electrochemical determination of superoxide anion radical and nitrite using Cu,ZnSOD immobilized on carbon nanotube in polypyrrole matrix.

@article{Rajesh2010SimultaneousED,
  title={Simultaneous electrochemical determination of superoxide anion radical and nitrite using Cu,ZnSOD immobilized on carbon nanotube in polypyrrole matrix.},
  author={Seenivasan Rajesh and Anantha Koteswararao Kanugula and Kalpana Bhargava and Govindaswamy Ilavazhagan and Srigiridhar Kotamraju and Chandran Karunakaran},
  journal={Biosensors & bioelectronics},
  year={2010},
  volume={26 2},
  pages={689-95}
}
A novel highly sensitive biosensor for the direct and simultaneous determination of superoxide anion radical (O2-) and nitrite (NO2-) was developed by incorporation of carbon nanotube (CNT) solubilized in nafion in polypyrrole (PPy) matrix on Pt electrode followed by immobilization of Cu,ZnSOD (SOD1) on it. The CNT/PPy nanocomposite electrode enhanced the immobilization of SOD1 and promoted the electron transfer of SOD1 minimizing its fouling effect. The surface morphological images of PPy and… CONTINUE READING