Simultaneous determination of the main metabolites of dipyrone by high-pressure liquid chromatography.

Abstract

A simple, rapid, and sensitive procedure is described for the determination of the main metabolites of dipyrone in plasma and urine. After adding isopropyl aminoantipyrine as internal standard and a deproteinizer the plasma of urine samples are alkalized and extracted with chloroform. The residue of the evaporated organic phase is dissolved in mobile phase… (More)

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