Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.

@article{ElSaharty2002SimultaneousDO,
  title={Simultaneous determination of terbinafine HCL and triamcinolone acetonide by UV derivative spectrophotometry and spectrodensitometry.},
  author={Yasser Shaker Ibrahim El-Saharty and Nagiba Yehya Hassan and Fadia Hussein Metwally},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2002},
  volume={28 3-4},
  pages={569-80}
}
A binary mixture of terbinafine hydrochloride and triamcinolone acetonide was determined by three different methods. The first one concerned with determination of both drugs using first derivative (D(1)) spectrophotometric technique at 297 and 274 nm over concentration ranges of 5-30 and 4-24 microg ml(-1), with mean percentage accuracies 99.90+/-0.67 and 100.25+/-0.49, respectively. The second method depends on ratio-spectra 1st derivative (RSD(1)) spectrophotometry at 298 and 248 nm over the… CONTINUE READING

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