Simultaneous determination of pancuronium, vecuronium and their related compounds using LC-ESI-MS.

@article{Usui2006SimultaneousDO,
  title={Simultaneous determination of pancuronium, vecuronium and their related compounds using LC-ESI-MS.},
  author={Kiyotaka Usui and Takanori Hishinuma and Hiroaki Yamaguchi and Toshihide Saga and Toshihiro Wagatsuma and Kunihiko Hoshi and Naoki Tachiiri and Kuniaki Miura and Junichi Goto},
  journal={Legal medicine},
  year={2006},
  volume={8 3},
  pages={
          166-71
        }
}
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18 Citations
Background Citations
2
Methods Citations
2

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18 Citations

Quantitative analysis of the aminosteroidal non-depolarizing neuromuscular blocking agent vecuronium by LC-ESI-MS: A Postmortem Investigation.

A quantitative method for the analysis of vecuronium and its active metabolite, 3-desacetylveCuronium, in blood and tissue samples was developed using liquid chromatography-electrospray ionization mass spectrometry operated in positive selected ion monitoring mode.

Stability indicating liquid chromatography method for the analysis of Vecuronium bromide: study of the degradation profile

Determination of Vecuronium Bromide in Pharmaceuticals: Development, Validation and Comparative Study of HPLC and CZE Analytical Methods

Vecuronium bromide is a neuromuscular blocking agent used for anesthesia to induce skeletal muscle relaxation. HPLC and CZE analytical methods were developed and validated for the quantitative…

Determination of muscle relaxants pancuronium and vecuronium bromide by capillary electrophoresis with capacitively coupled contactless conductivity detection

A novel capillary electrophoretic method for the separation of pancuronium (PM) and vecuronium (VM) ions utilizing capacitively coupled contactless conductivity detection was devised and validated and applied to the assay of PMB and VMB in commercial injection solutions.

A modification of the kinetic determination of pancuronium bromide based on its inhibitory effect on cholinesterase

The method developed was applied for PCBr determination in spiked serum and urine samples and in the urine taken during surgery and was proven to have good sensitivity, accuracy, and precision and can be considered suitable for clinical practice.

Determination of Pancuronium and Its Impurities in Pharmaceutical Preparation by LC with Charged Aerosol Detection

A novel, sensitive and simple liquid chromatography method with charged aerosol detection (LC-CAD) for the simultaneous assay determination of pancuronium and its impurities (dacuronium and…

Analysis of rocuronium in human whole blood and tissues using liquid chromatography-tandem mass spectrometry.

The validated method was applied to quantify the content of rocuronium in blood and a variety of tissues of a victim suspected of overdose and was successfully applied for the analysis of roCuronum in biological samples for forensic toxicology.

[Simultaneous determination of three quaternary ammonium muscle relaxants in blood by high performance liquid chromatography-tandem mass spectrometry].

A method based on high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was established for the simultaneous determination of the three quaternary ammonium muscle relaxants in blood and showed good linear relationships in each range, and all correlation coefficients (R2) were > 0996.

Mass Spectrometric and Contactless Conductivity Detection Approaches in the Determination of Muscle Relaxants by Capillary Electrophoresis

Novel and rapid capillary electrophoresis-coupled tandem mass spectrometry (CE-MS/MS) and capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4D) methods have…

A point of care screen printed potentiometric sensor for therapeutic monitoring of vecuronium

References

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