Simultaneous determination of levonorgestrel and two endogenous sex hormones in human plasma based on LC-MS/MS.

Abstract

BACKGROUND Levonorgestrel (LNG) is a commonly used emergency contraceptive which can effect sex hormone levels in female blood. The objective of this study was to develop and validate a specific and sensitive LC-MS/MS method for monitoring endogenous sex hormone levels (17β-estradiol and progesterone) in female plasma after administration of LNG. Results… (More)
DOI: 10.4155/bio-2015-0036

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