Simultaneous determination of four alkaloids in Lindera aggregata by ultra-high-pressure liquid chromatography-tandem mass spectrometry.

@article{Han2008SimultaneousDO,
  title={Simultaneous determination of four alkaloids in Lindera aggregata by ultra-high-pressure liquid chromatography-tandem mass spectrometry.},
  author={Zheng Han and Yunliang Zheng and Na Chen and L. Luan and Chang-xin Zhou and Lishe Gan and Yongjiang Wu},
  journal={Journal of chromatography. A},
  year={2008},
  volume={1212 1-2},
  pages={
          76-81
        }
}
A new separation and quantification method using liquid chromatography under ultra-high-pressure in combination with tandem mass spectrometry (MS/MS) was developed for simultaneous determination of four alkaloids in Lindera aggregata. The analysis was performed on an Acquity UPLC BEH C(18) column (50mmx2.1mm, 1.7microm particle size; Waters, Milford, MA, USA) utilizing a gradient elution profile and a mobile phase consisting of (A) water containing 10mM ammonium acetate adjusted to pH 3 with… Expand
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