Simultaneous determination of evodiamine and evodine in Beagle dog plasma using liquid chromatography tandem mass spectrometry.

Abstract

A sensitive, rapid, and specific liquid chromatography/tandem mass spectrometry assay has been established and validated for the quantitation of evodiamine and evodine in Beagle dog plasma. Plasma samples of 0.2 ml were processed by liquid-liquid extraction with n-hexane/ethyl acetate (2:1, v/v). Chromatographic separations were done on a Symmetry C18… (More)
DOI: 10.1080/10286020.2012.762357

Topics

Cite this paper

@article{Xia2013SimultaneousDO, title={Simultaneous determination of evodiamine and evodine in Beagle dog plasma using liquid chromatography tandem mass spectrometry.}, author={Yuan-yuan Xia and Hai-yu Xu and You-You Cai and Duan-yun Si and Changxiao Liu}, journal={Journal of Asian natural products research}, year={2013}, volume={15 3}, pages={235-43} }