Simultaneous detection of the antioxidant and pro-oxidant activity of dietary polyphenolics in a peroxidase system.

@article{Chan2003SimultaneousDO,
  title={Simultaneous detection of the antioxidant and pro-oxidant activity of dietary polyphenolics in a peroxidase system.},
  author={Tom S. Chan and Giuseppe Galati and Ananth Sekher Pannala and Catherine A. Rice-Evans and Peter James O'Brien},
  journal={Free radical research},
  year={2003},
  volume={37 7},
  pages={787-94}
}
The ability to reduce the peroxidase (myeloglobin/H2O2)-generated ABTS*+ [2,2'-azinobis-(3-ethylbenzthiazoline-6-sulfonic acid) radical cation] has been used to rank the antioxidant activity of various agents including dietary flavonoids and chalcones. Surprisingly, we found that in the presence of catalytic concentrations of the phenol B-ring containing flavonoids, apigenin, naringenin and the chalcone phloretin, the formation of the ABTS*+ was initially increased. The enhanced formation of… CONTINUE READING

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