Simultaneous depletion of tryptophan, tyrosine and phenylalanine as an experimental method to probe brain monoamine function in humans.

@article{Nathan2004SimultaneousDO,
  title={Simultaneous depletion of tryptophan, tyrosine and phenylalanine as an experimental method to probe brain monoamine function in humans.},
  author={Pradeep J. Nathan and J Hughes and Bernie V McInerney and Ben J. Harrison},
  journal={The international journal of neuropsychopharmacology},
  year={2004},
  volume={7 2},
  pages={171-6}
}
Brain monoamines are important regulators of affective and cognitive processes and are involved in the aetiology of a number of psychiatric disorders. While methods to probe serotonin and catecholamine function are established, limited methods are available to probe monoamine function as a whole in humans. In the current study, we examined if simultaneous depletion of monoamine precursors can be used as a possible probe of monoamine function. Ten healthy subjects were tested under two treatment… CONTINUE READING