Simultaneous deletion of pseudorabies virus tegument protein UL11 and glycoprotein M severely impairs secondary envelopment.

@article{Kopp2004SimultaneousDO,
  title={Simultaneous deletion of pseudorabies virus tegument protein UL11 and glycoprotein M severely impairs secondary envelopment.},
  author={Martina Kopp and Harald Granzow and Walter Fuchs and Barbara G. Klupp and Thomas C Mettenleiter},
  journal={Journal of virology},
  year={2004},
  volume={78 6},
  pages={3024-34}
}
The pseudorabies virus (PrV) proteins UL11, glycoprotein E (gE), and gM are involved in secondary envelopment of tegumented nucleocapsids in the cytoplasm. To assess the relative contributions of these proteins to the envelopment process, virus mutants with deletions of either UL11, gM, or gE as well as two newly constructed mutant viruses with simultaneous… CONTINUE READING