Simultaneous changes in the function and expression of beta 1 integrins during the growth arrest of poorly differentiated colorectal cells (LISP-1).

@article{Roela2003SimultaneousCI,
  title={Simultaneous changes in the function and expression of beta 1 integrins during the growth arrest of poorly differentiated colorectal cells (LISP-1).},
  author={Rosimeire Aparecida Roela and Maria Mitzi Brentani and Maria L{\'u}cia Hirata Katayama and Marco Antonio Sousa Reis and Miriam Hatsue Honda Federico},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2003},
  volume={36 8},
  pages={1091-9}
}
Cells usually lose adhesion and increase proliferation and migration during malignant transformation. Here, we studied how proliferation can affect the other two characteristics, which ultimately lead to invasion and metastasis. We determined the expression of beta 1 integrins, as well as adhesion and migration towards laminin-1, fibronectin, collagens type… CONTINUE READING