Simultaneous blockade of dopamine and noradrenaline reuptake promotes disadvantageous decision making in a rat gambling task

@article{Baarendse2012SimultaneousBO,
  title={Simultaneous blockade of dopamine and noradrenaline reuptake promotes disadvantageous decision making in a rat gambling task},
  author={P. Baarendse and C. Winstanley and L. Vanderschuren},
  journal={Psychopharmacology},
  year={2012},
  volume={225},
  pages={719-731}
}
  • P. Baarendse, C. Winstanley, L. Vanderschuren
  • Published 2012
  • Medicine, Psychology
  • Psychopharmacology
  • RationaleThe inability to make profitable long-term decisions has been implicated in several psychiatric disorders. There is emerging evidence to support a role for dopamine (DA) in decision making, but our understanding of the role of noradrenaline (NA) and serotonin (5-HT) in decision making, and of possible interactions between the three monoamines, is limited. Moreover, impulsivity has been associated with aberrant decision making, but the underlying mechanisms are incompletely understood… CONTINUE READING

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