Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.

Abstract

BACKGROUND Endothelial function is impaired in hypercholesterolemia and atherosclerosis. Based on mostly indirect evidence, this impairment is attributed to reduced synthesis or impaired biological activity of endothelium-derived nitric oxide (NO). It was the aim of this study to directly estimate and compare whole-body NO production in normo- and… (More)

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@article{Maas2008SimultaneousAO, title={Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia.}, author={Renke Maas and E Ricardo Schwedhelm and Lydia Kahl and Huige Li and Ralf A. Benndorf and Nicole L{\"u}neburg and Ulrich Foerstermann and Rainer H. B{\"o}ger}, journal={Clinical chemistry}, year={2008}, volume={54 2}, pages={292-300} }