Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC-MS in plasma after oral application of small doses of THC and cannabis extract.

@article{Nadulski2005SimultaneousAS,
  title={Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC-MS in plasma after oral application of small doses of THC and cannabis extract.},
  author={Thomas Nadulski and Frank Sporkert and Martin Schnelle and Andreas Michael Stadelmann and Patrik Roser and Tom Schefter and Fritz Pragst},
  journal={Journal of analytical toxicology},
  year={2005},
  volume={29 8},
  pages={782-9}
}
Besides the psychoactive Delta(9)-tetrahydrocannabinol (THC), hashish and marijuana as well as cannabis-based medicine extracts contain varying amounts of cannabidiol (CBD) and of the degradation product cannabinol (CBN). The additional determination of these compounds is interesting from forensic and medical points of view because it can be used for further proof of cannabis exposure and because CBD is known to modify the effects of THC. Therefore, a method for the simultaneous quantitative… CONTINUE READING