Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements.

@article{Gong1993SimultaneousAO,
  title={Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements.},
  author={Jian-ping Gong and Frank Traganos and Zbigniew Darzynkiewicz},
  journal={Cancer research},
  year={1993},
  volume={53 21},
  pages={5096-9}
}
The methods of cell cycle analysis that rely on DNA content measurements cannot discriminate between cells at different phases of the cycle if these cells have similar DNA content. This limitation can be circumvented by measurement of another cell cycle phase-specific cell constituent in addition to DNA content, followed by bivariate analysis of the correlated data. The aim of the present study was to explore the utility of a monoclonal antibody against the G2- and M phase-specific regulatory… CONTINUE READING

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