Simultaneous acute Marchiafava–Bignami disease and central pontine myelinolysis

@article{Tsai2018SimultaneousAM,
  title={Simultaneous acute Marchiafava–Bignami disease and central pontine myelinolysis},
  author={Chun-Yi Tsai and Po-Kai Huang and Poyin Huang},
  journal={Medicine},
  year={2018},
  volume={97}
}
Rationale: Marchiafava–Bignami disease (MBD) is a rare disease characterized by demyelination of the corpus callosum. It is most commonly seen in patients with chronic alcoholism. The clinical diagnosis of MBD can be difficult due to its nonspecific manifestation. Central pontine myelinolysis (CPM) occurs mostly as a complication of severe and prolonged hyponatremia, especially when corrected too rapidly. However, CPM can be associated with chronic alcoholism and its clinical presentation can… 
3 Citations
Marchiafava‑Bignami Disease: The Importance of Early Diagnosis and Treatment by a Multidisciplinary Team
TLDR
The case of a 34‑year‑old male with a 10‑year history of alcohol dependence who was admitted to the hospital, after having been found lying on the floor of his house, malnourished and with pressure ulcers on his chest and knees, is reported.
Simultaneous acute Marchiafava-Bignami disease and posterior reversible encephalopathy syndrome: a case almost misdiagnosed.
TLDR
A 49-year-old male alcoholic with both MBD and PRES who had a good prognosis after correct diagnosis and timely treatment is reported.
Marchiafava-Bignami disease: Report of three cases.
TLDR
Three patients who had history of chronic alcoholism, different clinical presentation and MRI findings consistent with the diagnosis of Marchiafava-Bignami disease are reported.

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