Simultaneous Qualitation and Quantitation of Chlorogenic Acids in Kuding Tea Using Ultra-High-Performance Liquid Chromatography–Diode Array Detection Coupled with Linear Ion Trap–Orbitrap Mass Spectrometer

@article{Che2016SimultaneousQA,
  title={Simultaneous Qualitation and Quantitation of Chlorogenic Acids in Kuding Tea Using Ultra-High-Performance Liquid Chromatography–Diode Array Detection Coupled with Linear Ion Trap–Orbitrap Mass Spectrometer},
  author={Yanyun Che and Zhibin Wang and Zhiyun Zhu and Yangyang Ma and Yaqiong Zhang and Wen Gu and Jiayu Zhang and Gaoxiong Rao},
  journal={Molecules},
  year={2016},
  volume={21}
}
Kuding tea, the leaves of Ilex Kudingcha C.J. Tseng, has been applied for treating obesity, hypertension, cardiovascular disease, hyperlipidemia, and so on. The chlorogenic acids (CGAs) in Kuding tea have shown excellent antioxidative, antiobesity, anti-atherosclerotic and anticancer activities. Nevertheless, the chemical profiles of CGAs in Kuding tea have not been comprehensively studied yet, which hinders further quality control. In the present study, a sensitive ultra-high-performance… Expand
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A strategy based on the UHPLC‐qTOF‐MS/MS‐oriented characterizition and UPLC‐DAD‐based quantification for systematic assessment of the quality homogeneity of Ilex kudingcha C. J. Tseng was established and provided a potential approach for holistic quality control. Expand
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