Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

@article{Mandel2008SimultaneousMO,
  title={Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases},
  author={Silvia A. Mandel and Tamar Amit and Orly Weinreb and Lydia Reznichenko and Moussa B. H. Youdim},
  journal={CNS Neuroscience \& Therapeutics},
  year={2008},
  volume={14}
}
Current therapeutic approaches for Alzheimer and Parkinson disease (AD and PD, respectively) are merely symptomatic, intended for the treatment of symptoms, but offer only partial benefit, without any disease‐modifying activity. Novel promising strategies suggest the use of antiinflammatory drugs, antioxidants, iron‐complexing molecules, neurotrophic factor delivery, inhibitors of the amyloid precursor protein (APP)‐processing secretases, gamma and beta (that generate the amyloid‐beta peptides… 
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