Simultaneous Estimation of Bisoprolol Fumarate and Hydrochlorothiazide in Tablet Dosage Form by RP-HPLC Method

@inproceedings{Patel2006SimultaneousEO,
  title={Simultaneous Estimation of Bisoprolol Fumarate and Hydrochlorothiazide in Tablet Dosage Form by RP-HPLC Method},
  author={Laxman J. Patel and Bhanubhai. N. Suhagia and Paresh B. Shah and Rajiv R. Shah},
  year={2006}
}
A simple, specific, accurate and precise reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of bisoprolol fumarate and hydrochlorothiazide in tablet dosage form. A lichrospher 100 C-18, 5 μm column 20 cm × 4.6 mm in isocratic mode, with mobile phase containing water, acetonitrile and tetrahydrofuran in proportion of 80:20:5 v/v/v were used. The flow rate was 1 ml/min, and effluent was monitored at 225 nm. The retention time of bisoprolol… CONTINUE READING
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