Simultaneous Bayesian gene tree reconstruction and reconciliation analysis.

  title={Simultaneous Bayesian gene tree reconstruction and reconciliation analysis.},
  author={Orjan Akerborg and Bengt Sennblad and Lars Arvestad and Jens Lagergren},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 14},
We present GSR, a probabilistic model integrating gene duplication, sequence evolution, and a relaxed molecular clock for substitution rates, that enables genomewide analysis of gene families. The gene duplication and loss process is a major cause for incongruence between gene and species tree, and deterministic methods have been developed to explain such differences through tree reconciliations. Although probabilistic methods for phylogenetic inference have been around for decades… CONTINUE READING
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