Simultaneous AFM topography and recognition imaging at the plasma membrane of mammalian cells.

@article{Chtcheglova2018SimultaneousAT,
  title={Simultaneous AFM topography and recognition imaging at the plasma membrane of mammalian cells.},
  author={Lilia A. Chtcheglova and P. Hinterdorfer},
  journal={Seminars in cell & developmental biology},
  year={2018},
  volume={73},
  pages={
          45-56
        }
}
Elucidation the nano-organization of membrane proteins at/within the plasma membrane is probably the most demanding and still challenging task in cell biology since requires experimental approaches with nanoscale resolution. During last decade, atomic force microscopy (AFM)-based simultaneous topography and recognition imaging (TREC) has become a powerful tool to quickly obtain local receptor nano-maps on complex heterogeneous biosurfaces such as cells and membranes. Here we emphasize the TREC… CONTINUE READING