Simulation of the in vivo resorption rate of β-tricalcium phosphate bone graft substitutes implanted in a sheep model.

@article{BashoorZadeh2011SimulationOT,
  title={Simulation of the in vivo resorption rate of β-tricalcium phosphate bone graft substitutes implanted in a sheep model.},
  author={Mahdieh Bashoor-Zadeh and Gamal Baroud and Marc Bohner},
  journal={Biomaterials},
  year={2011},
  volume={32 27},
  pages={
          6362-73
        }
}
A few years ago, a model was proposed to predict the effect of the pore architecture of a bone graft substitute on its cell-mediated resorption rate. The aim of the present study was to compare the predictions of the model with the in vivo resorption rate of four β-tricalcium phosphate bone graft substitutes implanted in a sheep model. The simulation algorithm contained two main steps: (1) detection of the pores that could be accessed by blood vessels of 50 μm in diameter, and (2) removal of… CONTINUE READING

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