Simulation of neuronal death and network recovery in a computational model of distributed cortical activity.

Abstract

OBJECTIVES The authors utilize a model of activity-dependent neuronal plasticity to study the interplay between synaptogenesis, neuronal death, and neurogenesis on the resulting pattern of neuronal connectivity. DESIGN A mathematical model of neuronal network activity was employed, with plasticity instantiated by an activity-dependent rewiring rule. In… (More)
DOI: 10.1097/JGP.0b013e318187137a

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@article{Rubinov2009SimulationON, title={Simulation of neuronal death and network recovery in a computational model of distributed cortical activity.}, author={Mikail Rubinov and Anthony R. McIntosh and Michael J. Valenzuela and Michael Breakspear}, journal={The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year={2009}, volume={17 3}, pages={210-7} }