Simulation of changes in diffusion related to different pathologies at cellular level after traumatic brain injury.

@article{Lin2016SimulationOC,
  title={Simulation of changes in diffusion related to different pathologies at cellular level after traumatic brain injury.},
  author={Mu Fei Lin and Hongjian He and Giovanni Schifitto and Jianhui Zhong},
  journal={Magnetic resonance in medicine},
  year={2016},
  volume={76 1},
  pages={290-300}
}
PURPOSE The goal of the current study was to investigate tissue pathology at the cellular level in traumatic brain injury (TBI) as revealed by Monte Carlo simulation of diffusion tensor imaging (DTI)-derived parameters and elucidate the possible sources of conflicting findings of DTI abnormalities as reported in the TBI literature. METHODS A model with three compartments separated by permeable membranes was employed to represent the diffusion environment of water molecules in brain white… CONTINUE READING

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