Simulation of automatic measurement of cell distribution inhomogeneity in clonogenic assays.

@article{Roudot2000SimulationOA,
  title={Simulation of automatic measurement of cell distribution inhomogeneity in clonogenic assays.},
  author={A.-C. Roudot and D. Parent-Massin},
  journal={In vitro & molecular toxicology},
  year={2000},
  volume={13 2},
  pages={89-98}
}
The use of hematopoietic progenitors in toxicology often requires scoring colonies, micro- and macroclusters, and evaluation of their distribution while taking into account their shape. Unfortunately, this evaluation is long and tedious, and classification errors may occur. Image analysis can improve the method if there is an automatic way of performing the classification analysis. It has been previously demonstrated that cell conglomerates can be automatically detected. The present paper… CONTINUE READING

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