Simulation of DNA damage after proton irradiation.

  title={Simulation of DNA damage after proton irradiation.},
  author={W. Friedland and P. Philip Jacob and Philipp Bernhardt and Herwig G. Paretzke and Michael Dingfelder},
  journal={Radiation research},
  volume={159 3},
The biophysical radiation track simulation model PARTRAC was improved by implementing new interaction cross sections for protons in water. Computer-simulated tracks of energy deposition events from protons and their secondary electrons were superimposed on a higher-order DNA target model describing the spatial coordinates of the whole genome inside a human cell. Induction of DNA double-strand breaks was simulated for proton irradiation with LET values between 1.6 and 70 keV/microm and various… CONTINUE READING

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