Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons

@inproceedings{Song2012SimulationEO,
  title={Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons},
  author={Fujian Song and Allan B. Clark and Max Oscar Bachmann and Jim Maas},
  booktitle={BMC medical research methodology},
  year={2012}
}
BACKGROUND Indirect treatment comparison (ITC) and mixed treatment comparisons (MTC) have been increasingly used in network meta-analyses. This simulation study comprehensively investigated statistical properties and performances of commonly used ITC and MTC methods, including simple ITC (the Bucher method), frequentist and Bayesian MTC methods. METHODS A simple network of three sets of two-arm trials with a closed loop was simulated. Different simulation scenarios were based on different… CONTINUE READING
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